This page contains links to raw 16S rRNA gene sequence data from our CDC-funded studies on using fecal minibioreactors and humanized microbiota mice to study the impact of interpersonal microbiome variation on disruption following antibiotic treatment and its potential impact on susceptibility to Clostridioides difficile infection.
16S rRNA Gene Sequencing Data:
- Sequence data for human fecal minibioreactors colonized with feces from healthy adults (n=7), healthy children (3-17 years old, n=3) or healthy elders (>65 years old, n=2) that were either untreated or treated with augmentin, azithromycin, cefaclor, ceftriaxone, ciprofloxacin, clindamycin, doxycycline, fidaxomicin, imipenem, metronidazole, sulfamethoxazole, or vancomycin.
- Sequence data from humanized microbiota Swiss-Webster, C57Bl6/J, or C3H/HeN mice colonized with feces from a healthy adult, healthy child or healthy elder that was either untreated or treated with azithromycin, cefaclor, ceftriaxone, clindamycin, or fidaxomicin.
- Sequence data for human fecal minibioreactors colonized with feces from a healthy adult, healthy child or healthy elder that was either untreated or treated with azithromycin, cefaclor, ceftriaxone, clindamycin, or fidaxomicin.
- Sequence data rom humanized microbiota C57Bl6/J mice colonized with feces from a healthy adult, healthy child or healthy elder that was either untreated or treated with azithromycin, cefaclor, ceftriaxone, clindamycin, or fidaxomicin.